Aldehyde-selective Wacker-type oxidation of unbiased alkenes enabled by a nitrite co-catalyst.
نویسندگان
چکیده
Breaking the rules: Reversal of the high Markovnikov selectivity of Wacker-type oxidations was accomplished using a nitrite co-catalyst. Unbiased aliphatic alkenes can be oxidized with high yield and aldehyde selectivity, and several functional groups are tolerated. (18) O-labeling experiments indicate that the aldehydic O atom is derived from the nitrite salt.
منابع مشابه
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عنوان ژورنال:
- Angewandte Chemie
دوره 52 43 شماره
صفحات -
تاریخ انتشار 2013